Mary 75, presents with gradual deterioration and clouding of her vision over the past few years. She has a history of poorly controlled Type 2 diabetes with Hba1c of 8.5%

What is your primary diagnosis?

  1. Cataracts

 What are the Causes of this presentation?

  1. Advancing age
  2. Diabetes
  3. Drugs incl Steroids as elucidated below
  4. Radiation – long exposure to UBV
  5. TORCH organisms
  6. Trauma
  7. Uveitis
  8. Smoking

 What classes of medications can precipitate this presentation?

  1. Corticosteroids
  2. Antipsychotics part Quetiapine
  3. Methotrexate
  4. Oral contraceptives
  5. Carbamazepine
  6. Thiazides

 What are the key features of history for this presentation?

  1. Blurry vision/ Difficulty reading
  2. Glare
  3. Halos
  4. Diplopia
  5. Yellowing of vision

 What are the key features of examination in this presentation?

  1. Unilateral pupil opacity
  2. Absence of red reflex
  3. Reduced visual acuity

 What are the complications of this presentation?

  1. Glaucoma
  2. Uveitis
  3. Falls
  4. Visual impairment
  5. Occupational implications
  6. Driving implications

 What is the Visual Acuity standard for an unrestricted private drivers licence?

  1. 6/12 in the best eye or both eyes

What is the Visual Acuity standard for an unrestricted commercial drivers licence?

  1. Better eye at least 6/9 and worse eye at least 6/18

What are the key features of management of this presentation? 

  1. Correction of risk factors
  2. Referral to ophthalmology for surgery
  3. Sunlight avoidance with sunglasses or hats

 What are the differentials of leukocoria in children?

  1. Retinoblastoma
  2. Congenital cataract
  3. retinal malformation
  4. retinopathy of prematurity
  5. retinal detachment
  6. Intraocular infection

What is the most important immediate step in management in leukocoria in children?

  1. Immediate referral to ophthalmologist

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