Carol is a 45 year old woman with a history of psoriasis who presents with nail pitting.
What are the causes of pitting of the nail plate?
- Psoriasis
- Alopecia Areata
- Atopic dermatitis
What are the pharmacological treatment options for nail psoriasis?
- Calcipotriol solution twice daily
- Topical high-potency corticosteroid solution or ointment as weekend pulses under cellophane occlusion at night
- Clobetasol propionate 8% in a lacquer vehicle twice daily for 3 weeks then twice weekly
- 5-fluorouracil cream twice daily.
What are some second line option for treatment of nail psoriasis?
- Intralesional triamcinolone acetonide injections into proximal nail folds.
- Localised phototherapy with UVB
- photochemotherapy (PUVA)
- methotrexate
- acitretin
- ciclosporin
Reading
- Murtaghs General Practice Chapter 129 – http://murtagh.mhmedical.com/content.aspx?bookid=1522§ionid=116046129
- Murtaghs Practice Tips – Chapter 8 – Nail Problems – http://murtagh.mhmedical.com/content.aspx?bookid=1920§ionid=143276631
Podcast
- GP Core Content Podcast Episode 150 – Dermatology | Nails