Barry is a 35-year-old man presented with sudden onset of a right red eye, severe eye pain in right eye only, worse when trying to read, tearing, photophobia, and headache. He has a history of back pain for the last year which he has not sought treatment for.

What is the most likely diagnosis in this presentation? (1)
- Anterior Uveitis
What are the differentials in this presentation? (5)
- Acute Angle Closure Glaucoma
- Acute Anterior Uveitis
- GCA
- Scleritis
- Episcleritis
- Conjunctivitis
What are the features of history in Anterior Uveitis? (8)
- Eye Pain
- Eye Redness
- Photophobia are typical
- Eye pain worse on reading
- Progressive over hours/days
- Blurred vision
- Watery eyes
- Headache
What are the features of examination in Anterior Uveitis? (8)
- Painful red eye
- Synechiae or iris nodules – irregular iris
- Pupil may react sluggishly
- Photophobia
- VA may be reduced
- Tearing
- Lid puffiness
- Eyelid drooping
- Keratic Precipitate
- Ciliary flush
- Corneal oedema
- Hypopyon
- Inflammatory cells in the vitreous
- Disc inflammation
- IOP is most often decreased
What are the most common categories of pathology causing of anterior uveitis? (3)
- Idiopathic
- Infections
- Autoimmune
What are the most common infections causing uveitis? (3)
- TB
- Syphilis
- HSV
- Varicella Zoster
What are the most common autoimmune causes of Uveitis? (5)
- Seronegative spondyloarthropathies
- Ankylosing spondylitis
- Acute anterior uveitis
- Psoriatic arthritis
- Reiters syndrome
- Inflammatory Bowel Disease
- Juvenile Rheumatic Arthritis
What initial investigations might you perform to ascertain the cause of this patient’s symptoms? (8)
- FBC
- LFT
- UEC
- ESR
- CRP
- ANA
- Rheumatoid factor
- Anti-CCP
- ENA
- Faecal Calprotectin
- HLA-B27 typing
- Sacroiliac Xray
- Spinal Xray
What are the most important initial steps in management? (2)
- Refer to an ophthalmologist
- Do not initiate treatment for recurrent uveitis in primary care
What are the most common complications of this presentation? (2)
- Cystoid macular oedema
- Secondary cataract
References
- patient.info
- Murtaghs
- Colour Atlas of Family Medicine
- Dynamed