SCCs are high yield.

Features on examination of Squamous Cell Carcinoma

  • Firm thickening of skin
  • Hard nodules
  • Ulcers with everted edge

Features on History of Squamous cell Carcinoma

  • Slowly enlarging
  • Sharply demarcated
  • thickened
  • Red
  • Plaque
  • Crusty
  • Ulcerate
  • Bleed

Management of Squamous cell carcinoma

  • Excision and  Biopsy with <x> mm margins.
  • Cryotherapy by double freeze thaw
  • Imiquamod – superficial
    • 90% cure rate if depth < 0.75mm
    • Cure 30% if 4mm or more

What are the contraindications for imiquamod?

  • Not on face
  • Not on head
  • Not for infiltrating BCC
  • Not for cystic BCC
  • Not for micronodular BCC
  • Not for morphoeic BCCs

What is on the PBS listing for Imiquamod?

Biopsy confirmed primary superficial BCC in patients with normal immune function

What is the application mode of imiquamod?

Five nights a week for 6 weeks